transcription profiles of marker genes predict the transdifferentiation relationship between eight types of liver cell during rat liver regeneration
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Transcription Profiles of Marker Genes Predict The Transdifferentiation Relationship between Eight Types of Liver Cell during Rat Liver Regeneration
OBJECTIVE To investigate the transdifferentiation relationship between eight types of liver cell during rat liver regeneration (LR). MATERIALS AND METHODS 114 healthy Sprague-Dawley (SD) rats were used in this experimental study. Eight types of liver cell were isolated and purified with percoll density gradient centrifugation and immunomagentic bead methods. Marker genes for eight types of ce...
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Decreases during Rat Liver Regeneration
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Liver regeneration (LR) after 70% partial hepatectomy (PH) represents a unique in vivo model of cell cycle and gene regulation. This study was conducted to characterize apoptosis-associated gene expression during LR. The results indicated that transcripts for both bcl-x and bcl-2 exhibited similar patterns of expression during LR with peaks at 6 h post-PH. In contrast, the major I .1 -kb bax tr...
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عنوان ژورنال:
cell journalجلد ۱۷، شماره ۲، صفحات ۳۳۹-۳۵۴
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